MySTYL'One
May 25, 2023
New paper from Ghent university.
External lubrication is a highly valuable alternative lubrication method as it minimizes the negative impact on tablet properties encountered when using internal lubrication. In current study, experiments were performed with automated external lubrication systems implemented in a compaction simulator and rotary tablet press using three lubricants (magnesium stearate (MgSt), sodium stearyl fumarate (SSF) and glyceryl dibehenate (DBHG)).
In conclusion, the potent...
New paper from Ghent university.
External lubrication is a highly valuable alternative lubrication method as it minimizes the negative impact on tablet properties encountered when using internal lubrication. In current study, experiments were performed with automated external lubrication systems implemented in a compaction simulator and rotary tablet press using three lubricants (magnesium stearate (MgSt), sodium stearyl fumarate (SSF) and glyceryl dibehenate (DBHG)).
In conclusion, the potential of external lubrication for implementation on production scale tableting equipment and during scale-up was demonstrated for multiple lubricants.
More information in the papers section.
You can also find related papers on externa lubrication:
#rotary tablet press #direct compression #external lubrication #Compaction simulation #tablet properties #magnesium stearate
MySTYL'One
May 9, 2023
Tablets & capsules dives into oral solid dosage forms and the opportunities and challenges in 2023 and beyond:
Materials-sparing
formulation development approaches enabled by compaction simulation will be
widely adopted. Rich information on the properties and performance of API and
blends can be collected using grams of material on a compaction simulator. Punch sticking, air entrapment, speed
effect, tooling design, and other process parameters can be studied to optimize
formulation and manufacturing process so that they are amenable for commercial
manufacturing.
Additional topics:
Full news available on Tablets & Capsules.
#tool management #Compaction simulation #material sparing #sustainability #Pharma 4.0 #customization #automation