Newsroom, your daily review

Keep up with the latest in the tableting community!


Showing posts tagged as : #STYL'One

Announcement

MySTYL'One

Jan. 26, 2023

Surface Characterization as a Tool for Identifying the Factors Affecting the Dissolution Rate of Amorphous Solid Dispersion Tablets


In this paper you will find a study explaining the interplay between the surface properties and the dissolution rate of ASD tablets. The paper is available in the PAPERS section.

Find others papers here and learn about

  • Understanding the Multidimensional Effects of Polymorphism, Particle Size and Processing for D-Mannitol Powders
  • Mean yield pressure from the in-die Heckel analysis is a reliable plasticity parameter
  • Fate of Tableted Freeze-Dried siRNA Lipoplexes in Gastrointestinal Environment

#contact angle #STYL'One #Wettability #surface free energy #dissolution rate

Announcement

MySTYL'One

Jan. 19, 2023

Evaluation of alternative methods to derive particle density from compression data


In this paper you will find a study on the methods by Sun and Krumme wich have been investigated in detail regarding their robustness against variations in tableting settings.The paper is available in the PAPERS section.

Find others papers here and learn about

  • Effect of Die Taper and Precompression on Air Entrapment during Tablet Compression
  • Air Entrapment during Tablet Compression – Diagnosis and Impact on Tableting Performance Assessed with a Compaction Simulator
  • Understanding the Multidimensional Effects of Polymorphism, Particle Size and Processing for D-Mannitol Powders

#contact angle #STYL'One #Wettability #surface free energy #dissolution rate

Announcement

MySTYL'One

Dec. 20, 2022

Hydrochlorothiazide/Losartan Potassium Tablet Prepared by Direct Compression


In this paper you will find a study that investigates on Hydrochlorothiazide/Losartan Potassium used to prepare compound tablets through the investigation of the compression and mechanical properties of mixed powders to determine the formulation and preparation factors. The paper is available in the PAPERS section.

Find others papers here and learn about

  • Pharmaceutical Development of Film-Coated Mini-Tablets with Losartan Potassium for Epidermolysis Bullosa
  • A mechanistic understanding of compres...

In this paper you will find a study that investigates on Hydrochlorothiazide/Losartan Potassium used to prepare compound tablets through the investigation of the compression and mechanical properties of mixed powders to determine the formulation and preparation factors. The paper is available in the PAPERS section.

Find others papers here and learn about

  • Pharmaceutical Development of Film-Coated Mini-Tablets with Losartan Potassium for Epidermolysis Bullosa
  • A mechanistic understanding of compression damage to the dissolubility of coated pellets in tablets
  • Investigation of Compressibility Characteristics of Paracetamol using Compaction Simulator

#STYL'One #mechanical properties #direct compression #dissolution rate #bioavailibility #compression properties

Announcement

MySTYL'One

June 29, 2022

A generalized image analytical algorithm for investigating tablet disintegration


The University of Copenhagen presents a work on an approach for development of the optimal tablet formulation as well as gaining an understanding on how the selection of excipients and manufacturing processes ultimately influences tablet disintegration.Medelpharm is part of this innovative project. Full paper available in the PAPERS section.

Find others papers here and learn about

  • Modeling of Disintegration and Dissolution Behavior of Mefenamic Acid Formulation Using Numeric Solution of Noyes-W...

The University of Copenhagen presents a work on an approach for development of the optimal tablet formulation as well as gaining an understanding on how the selection of excipients and manufacturing processes ultimately influences tablet disintegration.Medelpharm is part of this innovative project. Full paper available in the PAPERS section.

Find others papers here and learn about

  • Modeling of Disintegration and Dissolution Behavior of Mefenamic Acid Formulation Using Numeric Solution of Noyes-Whitney Equation with Cellular Automata on Microtomographic and Algorithmically Generated Surfaces
  • Predictive selection rule of favourable image processing methods for X-ray micro-computed tomography images of tablets
  • Pharmaceutical Development of Film-Coated Mini-Tablets with Losartan Potassium for Epidermolysis Bullosa

#STYL'One #Tablet disintegration #multivariate data analysis #tablet disintegration kinetics #image analysis #imaging

Announcement

MySTYL'One

April 11, 2022

Physicochemical Changes and Chemical Degradation of Gliclazide during Twin-Screw Melt Granulation


The present work details how the twin-screw melt granulation process affects the chemical stability and process-induced physicochemical changes of the drug. Full paper available in the PAPERS section.

Find others papers here and learn about

  • Structure-property relationship of Amorphous Maltitol as Tableting Excipient
  • Development of Coprocessed Chitin-Calcium Carbonate as Multifunctional Tablet Excipient for Direct Compression
  • Simulations of Drug Realease Profiles as a Function of Different Geometr...

The present work details how the twin-screw melt granulation process affects the chemical stability and process-induced physicochemical changes of the drug. Full paper available in the PAPERS section.

Find others papers here and learn about

  • Structure-property relationship of Amorphous Maltitol as Tableting Excipient
  • Development of Coprocessed Chitin-Calcium Carbonate as Multifunctional Tablet Excipient for Direct Compression
  • Simulations of Drug Realease Profiles as a Function of Different Geometrical Designs

#granulation process #STYL'One #Gliclazide #degradation #kneading element

Announcement

MySTYL'One

April 4, 2022

Pharmaceutical Development of Film-Coated Mini-Tablets with Losartan Potassium for Epidermolysis Bullosa


The present work details the development of an oral solid dosage form to address the rare disease epidermolysis bullosa, which can appear already in newborn children. Full paper available in the PAPERS section.

Find others papers here and learn about

  • Transfer and scale-up of the manufacturing of orodispersible mini-tablets from a compaction simulator to an industrial rotary tablet press
  • QbD approach formulation design for metformin HCI and evaluations
  • Tableting of mini-tablets in comparison with ...

The present work details the development of an oral solid dosage form to address the rare disease epidermolysis bullosa, which can appear already in newborn children. Full paper available in the PAPERS section.

Find others papers here and learn about

  • Transfer and scale-up of the manufacturing of orodispersible mini-tablets from a compaction simulator to an industrial rotary tablet press
  • QbD approach formulation design for metformin HCI and evaluations
  • Tableting of mini-tablets in comparison with conventionally sized tablets: A comparison of tableting properties and tablet dimensions

#STYL'One #stability #epidermolysis bullosa #losartan potassium #dry granulation #paediatrics #rare disease #mini-tablets #coating

Announcement

MySTYL'One

March 30, 2022

Why Tabletability Assessment Of Your Formulation Is A Fundamental Step Of Your Tablet Development ?


MySTYL'One user exclusive!

New bulletin available on fundamental step in a tablet development. This case study highlight how quickly excipients or powder blends can be compared thanks to tabletability profiles.

#bulletin #formulation #STYL'One #production #tabletability

Announcement

MySTYL'One

Feb. 7, 2022

Granutools Pharma User Club webinar - Replay available

On January 27th, 2022 Granutools organized their User Club Meeting for members of the pharmaceutical sector. 

This virtual meeting was the occasion to hear case studies presented by speakers who use Granutools equipment for their work. 

Delphine Ach-Hubert, formulation scientist at MEDELPHARM, presented case studies on particle size influence on tableting properties, using Granutools equipment and the STYL'One Evo compaction simulator. 

Replay available HERE

#webinar #STYL'One #Granutools #particle size

Feature article

MySTYL'One

Jan. 12, 2022

STYL'One Nano Live Demo


New event open to MySTYL'One members!

Join us for the STYL’One Nano Live Demo!

Wednesday January 19th, 4 pm - 5 pm (Paris Time)

#STYL'One Nano #STYL'One #live demo #online

Publish with us!