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Showing posts tagged as : #STYL'One evo

Feature article

MySTYL'One

Jan. 31, 2023

Webinar: "Assessing temperature influence on tablet quality attributes"

February  28th, 3pm (Paris Time)

"Assessing temperature influence on tablet quality attributes - Using a temperature-controlled die on the STYL’One Evo compaction simulator"

#STYL'One evo #compaction simulator #sticking #picking #temperature influence #webinar

Feature article

Pharmaceutical Manufacturer

Jan. 12, 2023

Customised excipient blends for capsule to tablet formulations

Dr. Sandeep Kumar, Formulation Development manager, Colorcon, sheds light on how selecting an excipient in early formulation development is critical to developing a robust scalable SOD formulation and can help the transition from capsule to tablet formulations.

#R&D #STYL'One evo #MEDELPHARM #containment

Video

Thermofisher Scientific

Nov. 23, 2022

Material matters: Material Science, Process Simulation and Modeling for Oral Solid Dosage Forms

With the ever-growing pressure to get new therapies to patients faster, predictive modeling and simulation tools are increasingly recognized as critical enabling technologies for accelerating drug product development. In the development of oral solid dosage forms, predictive modeling and simulation tools of the manufacturing processes can enhance process understanding, save on API supply, improve product quality, and reduce or eliminate many of the bottlenecks associated with empirical method...

With the ever-growing pressure to get new therapies to patients faster, predictive modeling and simulation tools are increasingly recognized as critical enabling technologies for accelerating drug product development. In the development of oral solid dosage forms, predictive modeling and simulation tools of the manufacturing processes can enhance process understanding, save on API supply, improve product quality, and reduce or eliminate many of the bottlenecks associated with empirical methods.

Each active pharmaceutical ingredient (API) has its own set of unique physical and chemical properties that can affect the success of product formulations and manufacturing routes. On account of this, the manufacturing process for solid dosage forms need to be thoroughly understood. Determining robust formulations and processes for a given compound requires a deep understanding of material science and powder behavior.

#R&D #STYL'One evo #Powder compaction #science lab #Material science

Announcement

MySTYL'One

July 22, 2022

On the complexity of predicting tablet capping


The present works demonstrated from a study to predict capping on biconvex tablets from a wide range of products (18 formulations, 8 of which presenting capping), using the properties characterized on defect-free flat-faced tablets (tensile strength, solid fraction, elastic recovery, etc.). The study is available in the PAPERS section.

Find others papers here and learn about

  • Use of impulse excitation technique for the characterization of the elastic anisotropy of pharmaceutical tablets
  • Enabling the direct compression of metformin hydrochloride through QESD crystallization
  • Role of Precompression in the Mitigation of Capping: A Case Study

#STYL'One evo #tablet #compaction #decision tree #capping

Video

CPhI Global Pharma Events

July 9, 2022

Flashback on Skyepharma conference on Compaction simulation at CPhI worldwide edition 2018

MySTYL'One members exclusive!

CPhI worldwide 2018

Conference in the ICSE theatre : Compression Simulation as a Powerful Quality by Design (QbD) Tool

Animated by Aline Moulin, Senior Project Manager - Pharmaceutical Development

#STYL'One evo #scale-up #optimization #QbD #compaction simulator #conference #prototype

Announcement

MySTYL'One

June 2, 2022

Radial die wall pressure measurement

MySTYL'One user exclusive!

New bulletin available on the methodology of MEDELPHARM Science Lab to characterize radial die wall pressure powders with instrumented die.

#die-wall #STYL'One evo #radial pressure #Instrumented Die

Announcement

MySTYL'One

April 22, 2022

Assess the impact of your granulation process parameters with the STYL'One Evo

MySTYL'One user exclusive!

New bulletin available on the methodology of MEDELPHARM Science Lab to study the effects of granulation critical process parameters on product quality attributes. A development of a new directcompression grade of excipient produced by granulation. 

#STYL'One evo #compactibility #bulletin #powder granulation #pressure #carr index #angle of repose #flowability

Announcement

MySTYL'One

June 17, 2021

Replay: “Impact of Geometrical Process Parameters on the Tab-in-Tab structure”

MySTYL'One member exclusive!

MySTYL’One Live session is now available for replay.

Please click here to access the video (registered users only).

The video presents a joint experimental and numerical study from University of Bordeaux and Skyepharma’s research teams.

The webinar is extended with a hands-on demo on the STYL’One Evo showing how to develop press-coated tablets.

#STYL'One evo #webinar #Tab-in-Tab

Feature article

MySTYL'One

March 4, 2021

Webinar transcript – External Lubrication: How to mitigate the impact of lubricants on your quality attributes

On February 17th, Cedrine de Backere, PhD Student from Ghent University (Belgium) presented her work on external lubrication and how to mitigate the impact of lubricants on quality attributes. Bruno Leclercq, MEDELPHARM’s Science Lab Head and Business Developer also presented innovations from MEDELPHARM on external lubrication. The session ended with a Q&A.

For those who could not join us you can freely access the transcript below.

Note: the registered members of MySTYL’One can access the full video of the webinar HERE. 

#STYL'One evo #external lubrication #transcript #webinar

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