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May 15, 2023
There is a wide portfolio of tablet presses on the market. The press design is depending on the application area. While in R&D only small quantities of powder formulations are available, high throughputs must be generated in the production area. It is a challenging task to assess the critical quality attributes for large scale productions already during the formulation development stage. Even though academia and industry are investigating and implementing scale-up of tablet production since decades, no consensus is found on how to do it best. This is due to the wide variety of formulations which are compressed. Also, the final tablet shapes and sizes do differ tremendously. From mini tablets in low volume to standard tablets in high-volume, a wide range must be covered depending on the application.