Newsroom, your daily review

Keep up with the latest in the tableting community!


Showing posts tagged as : #compaction simulator

Announcement

MySTYL'One

April 27, 2023

Formulation development and compaction of itraconazole amorphous solid dispersions tablets using quality by design principles

MySTYL'One user exclusive!

New bulletin available detailing processes used to achieve enhanced bioavailability of Itraconazole (ITZ):

  • amorphous solid dispersions of ITZ in a polymer matrix were produced using Hot Melt Extrusion
  • ASDS improve the poor solubility 
  • but impaires the tableting stage 

#kosmotropic salts #fast-screening approach #hot melt extrusion #Amorphous Solid Dispersion #compaction simulator #STYL'One Nano

Feature article

MySTYL'One

March 2, 2023

Webinar replay on demand - Assessing temperature influence on tablet quality attributes

Get access for this online event replay.

Date: Tuesday, February 28th, 2023
Time: 3pm (Paris time)
Duration: 60 minutes

"Assessing temperature influence on tablet quality attributes - Using a temperature-controlled die on the STYL’One Evo compaction simulator" - by Hanna Grumann, PhD student at the Institute of Pharmaceutics and Biopharmaceutics, Heinrich Heine University Düsseldorf, Germany under the supervision of Prof. Peter Kleinebudde.


#STYL'One evo #compaction simulator #sticking #picking #temperature influence #webinar

Announcement

MySTYL'One

March 28, 2023

Screening of lubricants towards their applicability for external lubrication

In this paper you will find a study that focuses on the ejection forces through external lubrication from a compaction simulator and shows how significantly lower lubricant concentrations are achieved than with internal lubrication.. The paper is available in the PAPERS section.

Find others papers here and learn about

  • Upscaling of external lubrication from a compaction simulator to a rotary tablet press
  • Impact of Lubrication on Key Properties of Orodispersible Minitablets in Comparison to Conven...

In this paper you will find a study that focuses on the ejection forces through external lubrication from a compaction simulator and shows how significantly lower lubricant concentrations are achieved than with internal lubrication.. The paper is available in the PAPERS section.

Find others papers here and learn about

  • Upscaling of external lubrication from a compaction simulator to a rotary tablet press
  • Impact of Lubrication on Key Properties of Orodispersible Minitablets in Comparison to Conventionally Sized Orodispersible Tablets
  • Impact of alternative lubricants on process and tablet quality for direct compression

#STYL'One #external lubrication #compaction simulator

Video

CPhI Global Pharma Events

July 9, 2022

Flashback on Skyepharma conference on Compaction simulation at CPhI worldwide edition 2018

MySTYL'One members exclusive!

CPhI worldwide 2018

Conference in the ICSE theatre : Compression Simulation as a Powerful Quality by Design (QbD) Tool

Animated by Aline Moulin, Senior Project Manager - Pharmaceutical Development

#STYL'One evo #scale-up #optimization #QbD #compaction simulator #conference #prototype

Announcement

MySTYL'One

June 2, 2022

Manufacturing of mini-tablets. Focus and impact of the tooling systems

The present work details the effect of the used tooling system on quality attributes during manufacturing mini-tablets. Full paper available in the PAPERS section.

Find others papers here and learn about

  • Transfer and scale-up of the manufacturing of orodispersible mini-tablets from a compaction simulator to an industrial rotary tablet press
  • Investigation of critical factors affecting mechanical characteristics of press-coated tablets using a compaction simulator
  • Along the Process Chain to Probiot...

The present work details the effect of the used tooling system on quality attributes during manufacturing mini-tablets. Full paper available in the PAPERS section.

Find others papers here and learn about

  • Transfer and scale-up of the manufacturing of orodispersible mini-tablets from a compaction simulator to an industrial rotary tablet press
  • Investigation of critical factors affecting mechanical characteristics of press-coated tablets using a compaction simulator
  • Along the Process Chain to Probiotic Tablets: Evaluation of Mechanical Impacts on Microbial Viability

#single-tip #multi-tip #Tooling system #compaction simulator #STYLOne #mini-tablets #Tableting properties

Announcement

MySTYL'One

April 11, 2022

Effect of feedframe on lubricant sensitivity during upscaling from a compaction simulator to a rotary tablet press

The present work details the effect of lubricant blending time and Paddle Speed of forced feeders on the tensile strength of lubricated microcrystalline cellulose (MCC) and lactose tablets. Full paper available in the PAPERS section.

Find others papers here and learn about

  • Prediction of the impact of lubrication on tablet compactibility
  • Transfer and scale-up of the manufacturing of orodispetsible mini-tablet from a compaction simulator to an industrial rotary tablet press
  • Tablet formulation devel...

The present work details the effect of lubricant blending time and Paddle Speed of forced feeders on the tensile strength of lubricated microcrystalline cellulose (MCC) and lactose tablets. Full paper available in the PAPERS section.

Find others papers here and learn about

  • Prediction of the impact of lubrication on tablet compactibility
  • Transfer and scale-up of the manufacturing of orodispetsible mini-tablet from a compaction simulator to an industrial rotary tablet press
  • Tablet formulation development focusing on the functional behaviour of water uptake and swelling

#Internal lubrication #Lubricant sensitivity #Upscaling #Powder compaction #compaction simulator #Direct Compression

Announcement

Skyepharma

March 15, 2021

STYL’One Evolution / Industrial rotary press correlation study on a tab-in-tab dosage form

MySTYL'One users exclusive!

Flashback on Aline Moulin (Skyepharma)'s presentation at CSF Cambridge 2018.

Discover the presentation of Skyepharma's study: "Correlation between STYL’One Evolution and an industrial rotary press on a tab-in-tab dosage form" directly in our library of bulletins (access is only open to STYL'One users)

#multilayer #controlled release #industrial rotary press #compaction simulator #tab-in-tab

Feature article

MySTYL'One

Nov. 2, 2020

Replay (Part 2) - STYL'One, a new approach to formulate tablets (Q&A session)

Read on the 2nd part of the transcript of MEDELPHARM's first live webinar on STYL'One technology.

On Tue. October 6th, Bruno Leclercq and Quentin Boulay presented STYL'One compaction simulation technologies and range of products to users and non-users of STYL'One .

The presentation was followed by a Q&A session on subjects ranging from lamination to minitablet weight consistency, external lubrication, ribbons, rotary tooling, punch force and tensile strength.

The full video of the webinar is still available here, or you can take a quick glance at the Q&A transcript below.

#Q&A #webinar #STYLOne #compaction simulator

Publish with us!