Newsroom, your daily review

Keep up with the latest in the tableting community!


Showing posts tagged as : #direct compression

Announcement

MySTYL'One

Jan. 19, 2023

Compressibility analysis as robust in-die compression analysis for describing tableting behaviour


In this paper you will find an investigation on the compressibility constant as an in-die method and has been compared with the Heckel analysis for describing the compressibility of materials during tableting. The paper is available in the PAPERS section.

Find others papers here and learn about

  • Mean yield pressure from the in-die Heckel analysis is a reliable plasticity parameter
  • Process Modeling and Simulation of Tableting—An Agent-Based Simulation Methodology for Direct Compression
  • Immediate-Re...

In this paper you will find an investigation on the compressibility constant as an in-die method and has been compared with the Heckel analysis for describing the compressibility of materials during tableting. The paper is available in the PAPERS section.

Find others papers here and learn about

  • Mean yield pressure from the in-die Heckel analysis is a reliable plasticity parameter
  • Process Modeling and Simulation of Tableting—An Agent-Based Simulation Methodology for Direct Compression
  • Immediate-Release Formulations Produced via Twin-Screw Melt Granulation: Systematic Evaluation of the Addition of Disintegrants

#direct compression #compression analysis #sensitivity analysis #compressibility constant #heckel #STYLOne

Announcement

MySTYL'One

Jan. 12, 2023

Understanding the Multidimensional Effects of Polymorphism, Particle Size and Processing for D-Mannitol Powders


In this paper you will find a study showing that surface characteristics and preprocessing can prevail over the impact of polymorphism on manufacturability for oral solid dosage forms. The paper is available in the PAPERS section.

Find others papers here and learn about

  • Novel Polyurethane Matrix Systems Reveal a Particular Sustained Release Behavior Studied by Imaging and Computational Modeling
  • Transformation Induite au cours d'un Procédé Industriel (TIPI) de compression directe: transition poly...

In this paper you will find a study showing that surface characteristics and preprocessing can prevail over the impact of polymorphism on manufacturability for oral solid dosage forms. The paper is available in the PAPERS section.

Find others papers here and learn about

  • Novel Polyurethane Matrix Systems Reveal a Particular Sustained Release Behavior Studied by Imaging and Computational Modeling
  • Transformation Induite au cours d'un Procédé Industriel (TIPI) de compression directe: transition polymorphique de la caféine et propriétés physiques des comprimés
  • Impact of micromeritic properties of an active pharmaceutical ingredient on its compaction behavior

#mannitol #roller compaction #direct compression #polymorphism #powder characterization #tabletability

Announcement

MySTYL'One

Dec. 20, 2022

Hydrochlorothiazide/Losartan Potassium Tablet Prepared by Direct Compression


In this paper you will find a study that investigates on Hydrochlorothiazide/Losartan Potassium used to prepare compound tablets through the investigation of the compression and mechanical properties of mixed powders to determine the formulation and preparation factors. The paper is available in the PAPERS section.

Find others papers here and learn about

  • Pharmaceutical Development of Film-Coated Mini-Tablets with Losartan Potassium for Epidermolysis Bullosa
  • A mechanistic understanding of compres...

In this paper you will find a study that investigates on Hydrochlorothiazide/Losartan Potassium used to prepare compound tablets through the investigation of the compression and mechanical properties of mixed powders to determine the formulation and preparation factors. The paper is available in the PAPERS section.

Find others papers here and learn about

  • Pharmaceutical Development of Film-Coated Mini-Tablets with Losartan Potassium for Epidermolysis Bullosa
  • A mechanistic understanding of compression damage to the dissolubility of coated pellets in tablets
  • Investigation of Compressibility Characteristics of Paracetamol using Compaction Simulator

#STYL'One #mechanical properties #direct compression #dissolution rate #bioavailibility #compression properties

Press review

MySTYL'One

Oct. 30, 2020

Roller compaction: new trends, challenges and solutions

Read the article from Catalent explaining the 3 known technologies to develop tablets:

- direct compression
- wet granulation
- dry granulation, 

with a focus on roller compaction, as it remains an effective solution for most APIs, in particular those as amorphous solid dispersions.

#direct compression #dry granulation #Roller compaction #wet granulation

Publish with us!