MySTYL'One
May 26, 2023
The SeDeM diagram expert system (DES) determines the suitability of excipients and active ingredients for Direct Compression and the ratio of API to excipient is calculated. The DC is most suitable as it saves time and makes process easy, but these technique excipients compensate for their poor flow. Thus, a new system was required to help reduce number of experiments and time for making an optimized direct compression tablet.
This review mainly focuses on various dosage forms like Solid, Sem...
The SeDeM diagram expert system (DES) determines the suitability of excipients and active ingredients for Direct Compression and the ratio of API to excipient is calculated. The DC is most suitable as it saves time and makes process easy, but these technique excipients compensate for their poor flow. Thus, a new system was required to help reduce number of experiments and time for making an optimized direct compression tablet.
This review mainly focuses on various dosage forms like Solid, Semisolid, Liquisolid, and Solidified liquid dosage forms. These techniques mainly characterize all substances using 12 parameters, resulting 12-sided regular polygon.
This new paper is available here on MySTYL’One.
MySTYL'One
May 25, 2023
New paper from Ghent university.
External lubrication is a highly valuable alternative lubrication method as it minimizes the negative impact on tablet properties encountered when using internal lubrication. In current study, experiments were performed with automated external lubrication systems implemented in a compaction simulator and rotary tablet press using three lubricants (magnesium stearate (MgSt), sodium stearyl fumarate (SSF) and glyceryl dibehenate (DBHG)).
In conclusion, the potent...
New paper from Ghent university.
External lubrication is a highly valuable alternative lubrication method as it minimizes the negative impact on tablet properties encountered when using internal lubrication. In current study, experiments were performed with automated external lubrication systems implemented in a compaction simulator and rotary tablet press using three lubricants (magnesium stearate (MgSt), sodium stearyl fumarate (SSF) and glyceryl dibehenate (DBHG)).
In conclusion, the potential of external lubrication for implementation on production scale tableting equipment and during scale-up was demonstrated for multiple lubricants.
More information in the papers section.
You can also find related papers on externa lubrication:
#rotary tablet press #direct compression #external lubrication #Compaction simulation #tablet properties #magnesium stearate
MySTYL'One
Oct. 30, 2020
Read the article from Catalent explaining the 3 known technologies to develop tablets:
- direct compression
- wet granulation
- dry granulation,
with a focus on roller compaction, as it remains an effective solution for most APIs, in particular those as amorphous solid dispersions.
#direct compression #dry granulation #Roller compaction #wet granulation